Topic: clinical development

Provide scientific and operational pharmacovigilance support for Beam’s therapeutic portfolio. Responsibilities span review of individual and cumulative safety data, signal assessment, risk management, aggregate safety reports and collaboration with clinical development teams. The director also oversees safety vendors and contributes to clinical and regulatory documents. The Cambridge role requires one to three days per week onsite.

Lead the medical and clinical development strategy for Beam’s metabolic disease franchise. The role shapes clinical plans and study protocols for base editing therapies, oversees ongoing trials and patient safety, and coordinates clinical and regulatory strategy. Responsibilities include mentoring physicians and clinical scientists and working with research teams on subsequent therapeutic programmes. This hybrid role requires residence within commuting distance of Cambridge, Massachusetts.

Direct clinical development of zugocaptagene-geleucel for autoimmune disease. Responsibilities include early- and late-stage trial strategy, protocol design, medical monitoring, interpretation of safety and efficacy data, and mentoring clinical development leads. The director also contributes to regulatory submissions and scientific presentations. Based in South Boston, Massachusetts, the employer describes at least three onsite days per week.