Mechanisms of drug resistance and tolerance in bacteria, fungi, and cancer
Mar 9–12, 2027
This symposium compares mechanisms of drug resistance, tolerance and persistence in bacteria, fungi and cancer. It explores how genetic change, non-genetic cellular plasticity, biochemistry and metabolism combine to let cells survive treatment. Themes include evolution under drug pressure, genome plasticity, stress responses, cellular fitness and the ecological context of drug responses. Efflux, microenvironmental effects and other extracellular contributors are considered alongside cellular states and biochemical mechanisms. By comparing systems across species, the programme aims to deepen un