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Topic: Environmental factors

Seminar
1 seminar

In Clinical Neurology and Epidemiology

Seminar · Clinical Neurology

Epigenetics and Dementia: Lessons From the 20-Year Indianapolis-Ibadan Dementia Study

Adesola Ogunniyi · University of Ibadan

Tue, Sep 29, 2020 · 15:00 UTC

Dementia is of global interest because of the rapid increase in both the number of individuals affected and the population at risk. It is essential that the risk factors be carefully delineated for the formulation of preventive strategies. Epigenetics refers to external modifications that turn genes "on" or "off”, and cross-cultural studies of migrant populations provide information on the interplay of environmental factors on genetic predisposition. The Indianapolis-Ibadan Dementia Study compared the prevalence, incidence and risk factors of dementia in African Americans and Yoruba to tease o