Investigate cell fate and tissue morphogenesis in the Cell Science accelerator, aiming to make multicellular behaviour predictable and programmable. Develop mechanistic and quantitative research using model organisms or organoids, supported by advanced microscopy, cell and molecular engineering, and modelling expertise. Coordinate scientific projects and supervise specialists as appropriate. The annualized salary range is USD 87,450–108,250; work is primarily onsite at 615 Westlake Avenue North, Seattle, with limited remote flexibility.
In Biology and Biophysics
Intrinsic Rhythms in a Giant Single-Celled Organism and the Interplay with Time-Dependent Drive, Explored via Self-Organized Macroscopic Waves
Eldad Afik · California Institute of Technology
Mon, Mar 28, 2022 · 00:00 UTC
Living Systems often seem to follow, in addition to external constraints and interactions, an intrinsic predictive model of the world — a defining trait of Anticipatory Systems. Here we study rhythmic behaviour in Caulerpa, a marine green alga, which appears to predict the day/night light cycle. Caulerpa consists of differentiated organs resembling leaves, stems and roots. While an individual can exceed a meter in size, it is a single multinucleated giant cell. Active transport has been hypothesized to play a key role in organismal development. It has been an open question in the literature wh
Over the past five years, our understanding of how mechanical processes act across multiple scales to direct morphogenesis has advanced significantly. Yet, there remain numerous open questions, including the role of mechanics in tissue shaping, cancer dissemination, and cellular aging. The From Molecules to Organs:The Mechanobiology of Morphogenesis conference will bring together world leaders in the fields of mechanobiology and morphogenesis. The three-day conference will span scales, from single molecules up to whole organisms.
Over the past five years, our understanding of how mechanical processes act across multiple scales to direct morphogenesis has advanced significantly. Yet, there remain numerous open questions, including the role of mechanics in tissue shaping, cancer dissemination, and cellular aging. The From Molecules to Organs:The Mechanobiology of Morphogenesis conference will bring together world leaders in the fields of mechanobiology and morphogenesis. The three-day conference will span scales, from single molecules up to whole organisms.