Mathematical Morphogenesis and Digital Twins Across Scales

Mathematical morphogenesis develops the theoretical foundations for understanding biological growth and form, with collective cell behaviour as a key focus: from molecular mechanisms, soft-matter physics and the mathematics of many-particle systems to multiscale models of developmental processes, wound healing, cancer progression and immune cell migration, using Drosophila, zebrafish and mammalian organoids as experimental platforms. Participants will discuss multiscale modelling of multicellular systems, translational models that make testable predictions, and data-driven and machine-learning methods for model development and analysis. Interdisciplinary focus groups address the hallmarks of coherent collective cell migration, how to evaluate competing models of collective cell behaviour, how to capture chemical and mechanical dynamics in deforming and growing 3D cellular domains, and how to calibrate and test models to establish verified digital twins of morphogenesis. Participation is by registration and acceptance through NITMB's workshop form. Participants based more than 50 miles from NITMB register by 31 May 2027; NITMB covers their travel, lodging, breakfast and lunch. Local participants (within 50 miles) register by 30 July 2027.