Topic: motor symptoms

Parkinson's Disease (PD) presents with debilitating motor and non-motor symptoms affecting patient quality of life (QoL). Deep Brain Stimulation (DBS) holds promise for mitigating motor symptoms but requires further investigation regarding its impact on QoL. The study explored DBS's effects on PD patients' QoL, employing clinical assessments, patient-reported outcomes, and longitudinal follow-up. A prospective cohort study was conducted involving 150 PD patients who underwent DBS surgery. Baseline assessments of motor and non-motor symptoms, alongside QoL, were recorded using standardized scal

This comprehensive study aimed to evaluate motor and non-motor symptoms of Parkinson's disease (PD) and patients with a scan without evidence of dopaminergic deficit (SWEDD) using diffusion tensor imaging (DTI) metrics. The study included 156 PD, 36 SWEDD, and 68 healthy control (HC) subjects, extracting comprehensive demographic data, motor variables, and full-scale non-motor tests from the PPMI database. Additionally, the study incorporated DTI's fractional anisotropy metric across three Substantia Nigra (SN) subregions. The results indicated notable differences in depressed mood percentages

Parkinson's disease is a progressive neurodegenerative disorder characterized by the appearance of motor and non-motor symptoms, resulting from the depletion of dopamine due to the degeneration of dopaminergic neurons. Unfortunately, there is currently no definitive test to confirm the diagnosis and no curative treatment for this disease.Our Epidemiological Study of the disease in Mauritania revealed several important findings. Age is a key factor in the incidence of the disease, with a significant increase in cases in individuals aged between 50 and 70. Parkinson's disease is also male-domina