SeminarNeuroscience
The tubulin code in neuron health and disease : focus on detyrosination
Marie-Jo Moutin
Grenoble Institute Neurosciences, Univ Grenoble Alpes, Inserm U1216, CNRS
Oct 10, 2025
SeminarNeuroscience
Charting the Proteome Landscape of Diverse Synapses In Vivo
Scott Soderling
Professor and Chair of Cell Biology, Professor of Neurobiology, George Barth Geller Distinguished Professor - Duke University
May 3, 2022
SeminarComputational Neuroscience
Integrative modeling of Paramecium, a swimming neuron
Romain Brette
Institut de la Vision, Université Pierre-and-Marie-Curie
Sep 23, 2020
Paramecium is a unicellular organism that swims in fresh water using cilia. When it is stimulated (mechanically, chemically, optically, thermally, etc), it often swims backward then turns and swims forward again: this is called the avoiding reaction. This reaction is triggered by a calcium-based action potential. For this reason, it enjoyed a period of glory in the 1970s as a model organism for neuroscience. I will describe the behavior and electrophysiology of this “swimming neuron”, then I will present our ongoing attempts at developing an integrative quantitative model of Paramecium.