Relating circuit dynamics to computation: robustness and dimension-specific computation in cortical dynamics
Shaul Druckmann · Stanford department of Neurobiology and department of Psychiatry and Behavioral Sciences
Wed, Apr 23, 2025 · 15:00 UTC
Neural dynamics represent the hard-to-interpret substrate of circuit computations. Advances in large-scale recordings have highlighted the sheer spatiotemporal complexity of circuit dynamics within and across circuits, portraying in detail the difficulty of interpreting such dynamics and relating it to computation. Indeed, even in extremely simplified experimental conditions, one observes high-dimensional temporal dynamics in the relevant circuits. This complexity can be potentially addressed by the notion that not all changes in population activity have equal meaning, i.e., a small change in