A Keystone Symposium bringing together single-cell genomics, spatial biology, perturbation technologies, computational methods, and clinical translation across high-burden diseases.
In Cell Biology and Genomics
The Research Luke Harland is establishing a new research group based in the Loke Centre for Trophoblast Research within the Department of Physiology, Development and Neuroscience at the University of Cambridge. The group investigates how specialised blood and vascular cell types arise during mammalian development and uses this knowledge to generate defined cell populations from pluripotent stem cells for mechanistic studies and tissue modelling. We aim to understand how developmental history shapes blood and vascular cell identity and function, and to apply this knowledge to build improved vas
Postdoctoral research with Stefanie Grosswendt’s group at the Max Planck Institute for Molecular Biomedicine, Münster, Germany. The laboratory investigates how neighbouring cells communicate and how these interactions influence gene regulation, cell fate and tissue function. Experimental and computational approaches combine single-cell genomics, CellMate-seq ligand–receptor measurements and imaging-based spatial transcriptomics. Projects examine neural crest development in mouse embryos and neuroblastoma, with complex in-vitro systems and bottom-up reconstruction used to connect communication