Topic: Genome engineering

Support genome-engineering experiments using CRISPR-based methods, including prime editing and transcriptional activation or inhibition. Laboratory work includes cloning, viral transduction, cell culture and molecular analysis, with applications to stem-cell-derived brain-cell models and chromatin profiling. The advertised appointment is full-time for twelve months. Apply through the university’s Varbi recruitment system by 20 October 2026.

One of the major roadblocks to medical progress in the field of neurodegeneration is the absence of animal models that fully recapitulate features of the human diseases. Unprecedented opportunities to tackle this challenge are emerging e.g. from genome engineering and stem cell technologies, and there are intense efforts to develop models with a high translational value. Simultaneously, single-cell, multi-omics and optogenetics technologies now allow longitudinal, molecular and functional analysis of human disease processes in these models at high resolution. During this workshop, 12 experts w