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Synaptic masks

2 ePosters

Newest first

Synaptic modulation facilitates adaptation in cortical networks

Ivan Bulygin, James Ferguson, Nicoleta Condruz, Tim Vogels · Bernstein Conference 2024

…often faster than can be explained by synaptic plasticity. One of the main candidates to account for such rapid changes is neuromodulation. We explore how modulation can assist a recurrent neural network to accommodate a range of variations of the tasks it is initially trained on. There are a number of approaches allowing for rapid acquisition of new tasks, for example, the neuronal gain modulation model [1]. However, we found that by affecting the input-output function of a neuron such an approach can neither address the variation of a

Computational Neuroscience

Synaptic low-rank modulation facilitates adaptation in cortical networks

Ivan Bulygin, James Ferguson, Tim Vogels · COSYNE 2023

…is thought to be possible by way of synaptic plasticity. Real-time control adaptation can only be achieved through faster processes such as neuromodulation. A number of neuromodulation models based on gain regulation have been proposed recently. But most of them utilize neuron-wide regulation and can not accommodate the simultaneous impact of different types of neurotransmitters on different parts of the dendritic tree. Models of synaptic gating and connectivity-tuning demonstrate that using enough additio

Computational Neuroscience