Transcription

…and measurements of morphology and transcription. Fellows develop independent projects during a three-year programme with a possible fourth year.

…It connects transcription, processing and modification, export and localisation, surveillance and decay, translation, and coupling between these processes. Sessions cover co-transcriptional and co-translational biology, RNA processing, RNP condensates, structure and regulation, and pathogens and therapeutics. The programme uses Europe/Berlin time: opening remarks on 13 October at 20:00, followed by the first keynote at 20:15; sessions begin at 09:00 on 14–15 October and 10:00 on 16 O

…individual copies of the gene, where transcription and its regulation take place stochastically. We recently combined single-molecule quantification of mRNA and gene loci to measure the transcriptional activity of an endogenous gene in individual Escherichia coli bacteria. When interpreted using a theoretical model for mRNA dynamics, the single-cell data allowed us to obtain the probabilistic rates of promoter switching, transcription initiation and