Vaccination

…PRRS variants and debate about vaccination as a control measure.

…characterizes B-cell responses after vaccination and infection, including the function and dynamics of memory B-cell reactivation. Its application to vaccination studies illustrates how single-cell measurements can inform HIV-1 vaccine design.

…display superior T-cell expansion upon vaccination. The improved T-cell responses in second ranked mice were dependent on the ability of synaptic communication in the brain. The brain circuits that control the position in the social hierarchy are beginning to em

After more than 4 million deaths worldwide, the ongoing vaccination to conquer the COVID-19 disease is now competing with the emergence of increasingly contagious mutations, repeatedly supplanting earlier strains. Following the near-absence of historical examples of the long-time evolution of infectious diseases under similar circumstances, models are crucial to exemplify possible scenarios. Accordingly, in the present work we systematically generalize the popular susceptible-infected-recovered model to account for mutations leading to repeatedly occurring new strains, which we coarse grain ba