Addiction Medicine ePosters

Substance use disorders (SUD) has a significant impact on human wellbeing and carries a high economic cost in the modern world. Astrocytes are known to participate in all major aspects of brain functions by regulating extracellular levels of neuroactive molecules. Notably, astrocytes were previously shown to…

Neuroinflammation mediated by toll-like receptors (TLRs) signaling pathway has a substantial role to morphine addiction. Αlpha-pinene is a member of the monoterpene family that has exhibited anti-inflammatory effects. This study aimed to examine the anti-inflammatory effects of alpha-pinene treatment on TLRs signaling…

Adinazolam (ADZ) is one of the benzodiazepine-type new psychoactive substances (NPSs) with anxiolytic, anticonvulsant, and antidepressant effects. Although it is previously reported that high dose of ADZ administration impaired psychomotor performance and memory, abuse potential and drug dependence of ADZ have not…

Drug addiction is a chronic relapsing disorder characterized by compulsive drug-seeking. There is lot of interest in gaining a better understanding of how acupuncture works in the brain to modulate addictive behaviors. The current study aims to discuss the neurobiological mechanisms underlying acupuncture’s…

Amphetamine is used in the therapy of mental disorders and for recreational purposes. However, repeated exposures lead to amphetamine sensitization (AS), which is associated with hyperdopaminergia, cognitive dysfunctions, and aberrant behavior. Notably, mounting evidence indicates that activation of group II…

Re-exposure to drug-associated spatial contexts often provokes drug craving and relapse. The hippocampus plays a critical role in drug associative learning, with a recent study reporting that drug-context associations were encoded in a specific group of CA1 place cells1. In addition to position (P) coding, both head…