Anesthesiology ePosters

Brain rhythms in the alpha frequency range [8Hz-12Hz] are present in idling conditions and sleep. They have also an important role in cognition, e.g. they modulate activity of task-irrelevant neural populations, and enhances selective attention among others. A prominent occipital alpha wave emerges in mammals when the…

Impaired cognition and pain after surgery contribute to prolonged hospital stays and increased mortality rates. Thus, the development of preemptive algorithms for reducing their impact should be prioritized. The main objectives of the present study were to evaluate the efficiency of using virtual reality (VR) to treat…

Deep anaesthetisation is an important surgical and explorative tool in the study of consciousness. Much work has been done to connect the deeply anaesthetised condition with decreased functional complexity. However, anaesthesia-induced unconsciousness is also a dynamic condition in which functional activity and…

The default mode network`s (DMN) can be investigated using default EEG reactivity (DER).The default oscillatory macrostate (DEM) is exemplified by the macrostate showing thehighest decrease in occurrence probability during intermittent photic stimulation (IPS).This study aimed to investigate DER, in the deeply sedated…

Anesthesia is ubiquitous in hospitals, yet a mechanistic understanding of how anesthetic drugs induce unconsciousness is lacking. A prominent hypothesis suggests that dynamic stability is critical to cortical function: awake brains are poised at a state that is sufficiently excitable for activity generation and…

Objective and quantitative assessment of the level of consciousness is a medical demand in clinics and a theoretical challenge to be addressed. Although a growing body of literature suggests different measures to distinguish the levels of consciousness, a systematic comparison of different measures is lacking. Such a…

Understanding the circuit mechanisms underlying the loss of consciousness during general anesthesia is a long-standing question. Activity within cortex drives conscious perception and, hence, the loss of consciousness is thought to result from the disconnection of cortex from subcortex. Here, we identify a change in…