Clinical Neurology workshops

Researchers from neuroscience, engineering and clinical practice will examine technologies for understanding brain function and treating disorders. Three tracks cover emerging neural recording and imaging methods, machine learning and brain-inspired computation, and clinical translation through neuroprosthetics, neuromodulation and brain-computer interfaces. The programme connects multiscale measurement, interpretable models, multimodal data and biomarkers with deployment challenges. Panels consider ethics, standards, clinical needs, careers and funding; posters, live demonstrations, exhibits and an aging-brain symposium support exchange. In-person at the National Housing Center, 1201 15th St NW, Washington, DC 20005, November 11–13. All times are US Eastern (America/New_York): November 11 registration 12:00, activities 13:00; November 12–13 registration 08:00, sessions 08:30; closing events end November 13 at 18:00. Regular fees: IEEE members USD 425, non-members USD 475; students USD 50/75 respectively. Early rates ended October 1. General poster/demo abstracts close October 19. Member and non-member registration is available through the event website.

Brain-restricted somatic variants can cause cortical malformations, developmental tumors and other focal epilepsies while escaping routine germline tests. This investigators workshop examines sensitive methods for detecting variants present in only a small fraction of cells. Sessions cover minimally invasive sampling, genomic assays, single-nucleus RNA sequencing and spatial analysis of brain tissue, then connect these approaches to genotype–phenotype relationships and mechanistic studies in human cells and mosaic mouse models. The aim is to improve diagnosis and identify more targeted therapeutic strategies. Saturday 5 December, 14:30–16:00 Mountain Standard Time (America/Denver). Part of the 2026 American Epilepsy Society Annual Meeting. In-person meeting registration and a free myAES account are required. Standard full-meeting rates are USD 800 for member scientists and USD 1,075 for non-member scientists; student rates are USD 250 and USD 360, respectively. Other professional and one-day categories are available. Seating priority goes to registered attendees.

Many epilepsies remain unexplained after exome or genome sequencing. This workshop investigates mechanisms that conventional testing may miss: somatic mosaicism, repeat expansions, epigenetic changes and microRNA regulation. It relates biological and technical detection limits to neuronal excitability, clinical heterogeneity and treatment resistance. Thematic presentations and an interactive panel address multi-omics study design, clinical phenotyping, biomarkers and therapeutic development, connecting molecular mechanisms to precision medicine and surgical decisions. Sunday 6 December, 08:30–10:00 Mountain Standard Time (America/Denver). Part of the 2026 American Epilepsy Society Annual Meeting. In-person meeting registration and a free myAES account are required. Standard full-meeting rates are USD 800 for member scientists and USD 1,075 for non-member scientists; student rates are USD 250 and USD 360, respectively. Other professional and one-day categories are available. Seating priority goes to registered attendees.

This investigators workshop examines adeno-associated virus gene therapies for epilepsy from design and animal testing through clinical translation. Research examples concern Lafora disease, SCN1B-related Dravet syndrome and SLC6A1-related neurodevelopmental disorder. The panel considers treatment efficacy, seizure-associated adverse effects and AAV toxicity, alongside strategies for overcoming current limitations. Discussion also covers biomarkers, scalability and the evidence needed to advance candidates beyond preclinical studies. Sunday 6 December, 14:00–15:30 Mountain Standard Time (America/Denver). Part of the 2026 American Epilepsy Society Annual Meeting. In-person meeting registration and a free myAES account are required. Standard full-meeting rates are USD 800 for member scientists and USD 1,075 for non-member scientists; student rates are USD 250 and USD 360, respectively. Other professional and one-day categories are available. Seating priority goes to registered attendees.

This workshop connects genomic discovery with prediction of epilepsy outcomes. It examines genome-based multi-omics in multigenerational cohorts, multimodal deep learning that combines clinical and genomic information to predict antiseizure medication response, and polygenic risk scores integrated with machine learning to estimate disease severity and seizure control. The presentations link these complementary approaches to the problem of clinical heterogeneity and assess their practical role in more individualized treatment. Sunday 6 December, 14:00–15:30 Mountain Standard Time (America/Denver). Part of the 2026 American Epilepsy Society Annual Meeting. In-person meeting registration and a free myAES account are required. Standard full-meeting rates are USD 800 for member scientists and USD 1,075 for non-member scientists; student rates are USD 250 and USD 360, respectively. Other professional and one-day categories are available. Seating priority goes to registered attendees.

This practical workshop explains how to establish chronic video-EEG recordings in rodent epilepsy models, from equipment and electrode placement to seizure monitoring and data management. Analysis ranges from spike and seizure quantification to machine learning. A second component introduces Motion Sequencing (MoSeq), an unbiased method for identifying and measuring behavior from video, with workflows for studying seizures, behavioral changes and associated conditions. Participants examine the hardware, software and implementation choices needed to introduce both approaches into their laboratories. Monday 7 December, 10:00–11:30 Mountain Standard Time (America/Denver). Part of the 2026 American Epilepsy Society Annual Meeting. In-person meeting registration and a free myAES account are required. Standard full-meeting rates are USD 800 for member scientists and USD 1,075 for non-member scientists; student rates are USD 250 and USD 360, respectively. Other professional and one-day categories are available. Seating priority goes to registered attendees.

Connect neuromuscular diagnosis with therapeutic decision-making through clinical lectures, interactive case workshops and participant case reports. The live programme addresses muscle imaging, channelopathies, myasthenic syndromes, muscular dystrophies and metabolic disorders, alongside clinical-trial methods and treatment challenges in settings with limited resources. Each day includes a 90-minute case-based workshop and discussion with experts, complemented by a library of recorded teaching. 14–16 December, 15:00–19:00 each day; Europe/Paris (CET, UTC+01:00). Entirely online, with up to 200 participants working in neuromuscular disorders. Applications require a CV and a short professional biography by 20 November. Fees including VAT: €250 regular or €1,000 industry; payment is due 10 December.

The programme follows memory mechanisms from molecular and cellular processes through synapses, microcircuits and distributed brain networks. It connects engram formation and synaptic plasticity with encoding, consolidation, persistence and flexibility. Sessions examine transcriptional, translational, epigenetic and RNA regulation, together with neuromodulation, before considering circuit vulnerability and memory disruption in neurodegenerative and neuropsychiatric disorders. Novel methods and unresolved questions connect the different biological scales. A satellite symposium on synapses and cognition takes place on 26 April. On-site and virtual participation are available; applicants submit an abstract or a brief statement of interest and are selected for scientific relevance.