Postdoctoral scholarship (2 years) within Non-canonical DNA structures

A two-year, full-time postdoctoral scholarship in the Department of Medical Biochemistry and Biophysics, Umeå University, within the project "Studies on non-canonical DNA structures", supervised by Professor Nasim Sabouri. G-quadruplexes (G4s) and i-motifs are alternative DNA structures that form in guanine- and cytosine-rich regions. The project explores how they interact with proteins and drug-like molecules and links their molecular properties to roles in genome function, health and disease, including possible new avenues for cancer research. The scholar will use fluorescence microscopy and next-generation sequencing to study G4s and i-motifs in cells, biophysical and biochemical methods including NMR, circular dichroism, real-time PCR and primer extension assays, and will examine how cancer drug candidates interact with these structures. Start January 2027 or by agreement.

Applicants must hold a doctoral degree or an equivalent foreign degree by the time of the award decision. Priority goes to candidates whose doctorate was completed no more than three years before the application deadline; earlier degrees can be considered for special reasons such as illness, parental leave, union appointments, military service or clinical practice.