Histopathology ePosters

Wasteosomes (or corpora amylacea) appear in the human brain with advancing age and in some neurodegenerative diseases. They have been proposed to accumulate waste substances and to contribute to a brain-cleaning mechanism. In this context, wasteosomes may have the potential to entrap some of the proteins that misfold,…

Acute Ischemic Stroke (AIS) is a major cause of death and disability worldwide. Mechanical thrombectomy to remove clots from cerebral vasculature represents a unique opportunity to study characteristics and biological patterns of stroke pathophysiology. There is marked heterogeneity in clots and great interest in…

Lead (Pb), a ubiquitous, non-biodegradable heavy metal contaminant, has significant impact on human and animal health. The adverse effect of lead on avian health and productivity has received little attention, considering the fact that they are sentinels. Alchornea laxiflora (Benth), family Euphorbiaceae, grows…

Wasteosomes (or corpora amylacea) appear in the human brain during aging and in some neurodegenerative conditions. They entrap waste substances originated from different cell types and can be released from the brain to the cerebrospinal fluid (CSF). Their presence in the CSF was described using electron microscopy,…

A link between type 2 diabetes mellitus and neurodegeneration has been suggested for decades. Diabetes-associated cognitive dysfunction has been linked to chronic hyperglycemia, oxidative stress, neuroinflammation, cholinergic dysfunction, and neuronal degeneration. We investigated the neuroprotective activity of a…

The liver, responsible for regulating the metabolism of the body; the kidney, the most important organ for waste elimination, and the spleen, in charge of filtering the blood and producing lymphocytes, are now considered to have clearance functions in Alzheimer’s disease (AD) eliminating Aβ from the brain. In the…

Hydrocephalus is associated with raised intracranial pressure (ICP) and has been implicated as the cause of endocrine dysfunction. Raised ICP results in distension of the third ventricle leading to compression of diencephalic structures and the hypothalamic-hypophyseal pathway. In this study, we aimed to assess the…