5 results
The Nirschl laboratory develops AI methods for human neurodegenerative disease. Projects combine whole-slide pathology, clinical and imaging records, molecular measurements and spatial omics to study tissue phenotypes and validate biomarkers in Alzheimer’s and Lewy body diseases. Responsibilities include model development and evaluation, reproducible…
Closes
The Institute for Neurodegenerative Diseases at UCSF, in the Sandler Neurosciences Center at Mission Bay, studies how the conformational heterogeneity, maturation and transmission of proteopathic assemblies (prions) of tau, amyloid-beta and alpha-synuclein differ across neural cell types and diseases. The Professional Researcher helps manage and contributes…
Closes
Develop machine-learning methods for quantitative neuropathology within the Brain Health initiative. Integrate histology, spatial molecular data, MRI and clinical information to investigate brain-disease mechanisms and progression. The role includes computer-vision models, multimodal learning, Bayesian and causal models, scientific collaboration and open…
Develop scalable machine-learning methods and infrastructure for the Brain Health initiative. Integrate digital histology, spatial transcriptomics, MRI and clinical data to model brain-disease progression at cellular resolution. Responsibilities include foundation models, distributed training, robust data pipelines and open-source scientific tools. This…
Develop machine-learning methods for sparse three-dimensional reconstruction of virtual histology from X-ray phase-contrast tomography. Work includes imaging breast biopsy specimens, constructing data pipelines, designing reconstruction algorithms and comparing results with standard histology. The doctoral researcher joins academic and clinical…
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