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Nmc4 Short Talk Transient

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Seminar✓ Recording AvailableNeuroscience

NMC4 Short Talk: Transient neuronal suppression for exploitation of new sensory evidence

Maxwell Shinn

Postdoctoral Researcher

University College London

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Wednesday, December 1, 2021

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Wednesday, December 1, 2021

2:00 PM America/New_York

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Host: Neuromatch 4

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Abstract

Decision-making in noisy environments with constant sensory evidence involves integrating sequentially-sampled evidence, a strategy formalized by diffusion models which is supported by decades behavioral and neural findings. By contrast, it is unknown whether this strategy is also used during decision-making when the underlying sensory evidence is expected to change. Here, we trained monkeys to identify the dominant color of a dynamically refreshed checkerboard pattern that doesn't become informative until after a variable delay. Animals' behavioral responses were briefly suppressed after an abrupt change in evidence, and many neurons in the frontal eye field displayed a corresponding dip in activity at this time, similar to the dip frequently observed after stimulus onset. Generalized drift-diffusion models revealed that behavior and neural activity were consistent with a brief suppression of motor output without a change in evidence accumulation itself, in contrast to the popular belief that evidence accumulation is paused or reset. These results suggest that a brief interruption in motor preparation is an important strategy for dealing with changing evidence during perceptual decision making.

Topics

checkerboard patterndecision-makingdiffusion modelsdrift diffusion modelevidence accumulationfrontal eye fieldmotor suppressionneural activityperceptual decision-makingprimatessensory evidencevision

About the Speaker

Maxwell Shinn

Postdoctoral Researcher

University College London

Contact & Resources

Personal Website

maxshinnpotential.com

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