World Wide relies on analytics signals to operate securely and keep research services available. Accept to continue, or leave the site.
Review the Privacy Policy for details about analytics processing.
Postdoctoral Researcher
University College London
Showing your local timezone
Schedule
Wednesday, December 1, 2021
2:00 PM America/New_York
Seminar location
No geocoded details are available for this content yet.
Recording provided by the organiser.
Format
Recorded Seminar
Recording
Available
Host
Neuromatch 4
Seminar location
No geocoded details are available for this content yet.
Decision-making in noisy environments with constant sensory evidence involves integrating sequentially-sampled evidence, a strategy formalized by diffusion models which is supported by decades behavioral and neural findings. By contrast, it is unknown whether this strategy is also used during decision-making when the underlying sensory evidence is expected to change. Here, we trained monkeys to identify the dominant color of a dynamically refreshed checkerboard pattern that doesn't become informative until after a variable delay. Animals' behavioral responses were briefly suppressed after an abrupt change in evidence, and many neurons in the frontal eye field displayed a corresponding dip in activity at this time, similar to the dip frequently observed after stimulus onset. Generalized drift-diffusion models revealed that behavior and neural activity were consistent with a brief suppression of motor output without a change in evidence accumulation itself, in contrast to the popular belief that evidence accumulation is paused or reset. These results suggest that a brief interruption in motor preparation is an important strategy for dealing with changing evidence during perceptual decision making.
Maxwell Shinn
Postdoctoral Researcher
University College London
Contact & Resources
neuro
neuro
The development of the iPS cell technology has revolutionized our ability to study development and diseases in defined in vitro cell culture systems. The talk will focus on Rett Syndrome and discuss t
neuro
Pluripotent cells, including embryonic stem (ES) and induced pluripotent stem (iPS) cells, are used to investigate the genetic and epigenetic underpinnings of human diseases such as Parkinson’s, Alzhe