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Synapses Shadows Stress Contagion

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Seminar✓ Recording AvailableNeuroscience

Synapses, Shadows and Stress Contagion

Jaideep Bains

Dr.

Professor, University of Calgary, Hotchkiss Brain Institute, Department of Physiology and Pharmacology

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Sunday, November 28, 2021

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Sunday, November 28, 2021

12:00 PM Canada/Central

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Host: Manitoba Neuroscience Network

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Abstract

Survival is predicated on the ability of an organism to respond to stress. The reliability of this response is ensured by a synaptic architecture that is relatively inflexible (i.e. hard-wired). Our work has shown that in naive animals, synapses on CRH neurons in the paraventricular nucleus of the hypothalamus are very reluctant to modification. If animals are stressed, however, these synapses become willing to learn. This seminar will focus on mechanisms linking acute stress to metaplastic changes at glutamate synapses, and also show how stress, and these synaptic changes can be transmitted from one individual to another.

Topics

CRH neuronsbehaviourglutamatemetaplasticityparaventricular nucleusplasticitystressstress contagionsynapsesynapsessynaptic architecturesynaptic modification

About the Speaker

Jaideep Bains

Dr.

Professor, University of Calgary, Hotchkiss Brain Institute, Department of Physiology and Pharmacology

Contact & Resources

Personal Website

stressynomics.com

@stressynomics

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twitter.com/stressynomics

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