AI-driven cholinergic theory enables rapid and robust cortex-wide learning
Maija Filipovica, Kevin Kermani Nejad, Will Greedy, Heng Wei Zhu, Rui Ponte Costa · COSYNE 2023
Sat, Mar 11, 2023
The cholinergic system has been associated with learning, but also with cognitive decline in dementia, aging and injury. Yet, to date, no computational models have been put forward to explain how the cholinergic system contributes to both learning and cognitive decline. Here we introduce a model that combines a recently proposed model of cortex-wide credit assignment with a cholinergic adaptive module based on adaptive deep learning rules. According to this model, the cholinergic system opens a cortex-wide gate for learning, but its end effect is controlled by local adaptive processes. Using a