Topic: Alzheimer’s dementia

Brain volume is commonly found in dementia both Alzheimer’s dementia (AD) and non-Alzheimer’s dementia (NAD). Clinical decision-making could be supported by identifying differences in brain parameters. This study investigates brain volume differences among individuals with normal cognition (NC), AD, and NAD using structural magnetic resonance imaging (MRI) and automated analysis with FreeSurfer. The aim is to identify brain parameters to differentiate between each group. A total of 76 participants were categorized into NC, AD, and NAD groups, and their brain scans were processed to obtain abso

Dementia is a prevalent and, based on severity, disabling neurocognitive disorder that primarily affects people older than 65 years of age. There is an increasingly emerging need to identify specific markers of dementia for interventions before disease progression. Irisin is a myokine produced during exercise with multiple effects on various organs, including a neuroprotective role on brain. Here, we investigated the involvement of irisin in patients with dementia biologically classified according to the Amyloid-β-Tau-Neurodegeneration classification system. Serum and cerebrospinal fluid (CSF)