Activity of distinct excitatory populations in prefrontal cortex during decision making in mice
The prefrontal cortex (PFC) is known to be involved in working memory, executive control, attention, and decision making. It integrates internal information and states with external information from the environment which results in timely and appropriate behavioral responses. It remains unknown how distinct excitatory cell types within PFC contribute to population activity and behavior. We investigate two major excitatory cell types within the PFC - extratelencephalic (ET) and intratelencephalic (IT) neurons. Anatomical analysis in transgenic mouse lines shows that ET neurons project to subcor