Topic: glioblastoma

Full-time postdoctoral research appointment in glioblastoma research at WEHI and within the Brain Cancer Centre network. The Ross Laybutt Fellowship supports an early-career researcher through significant brain-cancer projects, new experimental skills, mentorship, leadership development and scientific networking. The initial appointment lasts two years; any later fellowship-supported employment depends on funding and future recruitment processes. The advertised Research Employee Level A6–A8 salary is AUD 107,194–115,059, with 12% superannuation and an additional matching contribution of up to

Gladstone-UCSF Institute of Genomic Immunology Seminar by Christine Brown, PhD (Deputy Director, T Cell Therapeutics Research Laboratories) on developing and refining redirected CAR T cells for malignant brain tumors, including glioblastoma, tumor heterogeneity, immunosuppressive microenvironments, delivery routes, and manufacturing.

Astrocytes release glutamate by regulated exocytosis in health and disease Vladimir Parpura, International Translational Neuroscience Research Institute, Zhejiang Chinese Medical University, Hangzhou, P.R. China Parpura will present you with the evidence that astrocytes, a subtype of glial cells in the brain, can exocytotically release the neurotransmitter glutamate and how this release is regulated. Spatiotemporal characteristic of vesicular fusion that underlie glutamate release in astrocytes will be discussed. He will also present data on a translational project in which this release pathwa

Glioblastoma cells trigger pharmacoresistant seizures that may promote tumor growth and diminish the quality of remaining life. To define the relationship between growth of glial tumors and their neuronal microenvironment, and to identify genomic biomarkers and mechanisms that may point to better prognosis and treatment of drug resistant epilepsy in brain cancer, we are analyzing a new generation of genetically defined CRISPR/in utero electroporation inborn glioblastoma (GBM) tumor models engineered in mice. The molecular pathophysiology of glioblastoma cells and surrounding neurons and untra

Understanding the mechanisms underlying neurological disorders and offering fresh viewpoints and remedies, neuroscientists must bridge the gap between emerging technology and experimental research. We computed the cell migration ratio of confocal pictures of astrocytes and glioblastoma (GBM) in our recent study. The primary goal is to comprehend how astrocyte placement in the 3D cell culture model influences GBM migration. For image processing applications, there are numerous computational tools available. MATLAB provides an extensive library and the ability to create new, bespoke funct