Seminar, Hosted by Athens Neuroscience
Astrocytes release glutamate by regulated exocytosis in health and disease
Professor Vladimir Parpura
Distinguished Professor Zhejiang Chinese Medical University and Director of the International Translational Neuroscience Research Institute, Hangzhou, P.R. China
- Neuroscience, Cell Biology and
Abstract
Astrocytes release glutamate by regulated exocytosis in health and disease
Vladimir Parpura, International Translational Neuroscience Research Institute, Zhejiang Chinese Medical University, Hangzhou, P.R. China
Parpura will present you with the evidence that astrocytes, a subtype of glial cells in the brain, can exocytotically release the neurotransmitter glutamate and how this release is regulated. Spatiotemporal characteristic of vesicular fusion that underlie glutamate release in astrocytes will be discussed. He will also present data on a translational project in which this release pathway can be targeted for the treatment of glioblastoma, the deadliest brain cancer.