Topic: immune activation

This conference examines alcohol-related disease across organs and biological scales. It connects mitochondrial dysfunction, cellular aging, immune activation, inflammation and microbiome interactions with injury in the liver, gut, brain and cardiovascular system and with cancer. Organoids and other experimental platforms support discussion of therapeutic strategies, alongside integrated treatment of alcohol use disorder and end-organ damage. Talks, poster sessions and discussion focus on emerging and unpublished research. Applicants need a science or engineering bachelor’s degree or equivalen

This panel examines why strong immunogenicity in cancer-vaccine development does not always translate into clinical benefit. Prasun Chakraborty, Nora Disis and Timothy Spear compare delivery strategies aimed at the immune system or the tumour and discuss trade-offs between platforms. The programme considers how manufacturing limits and combination regimens constrain feasible approaches, and how delivery decisions influence immune activation, clinical translation and production at scale.