Topic: melatonin

Laboratory studies have shown that meaningful changes in light exposure lead to phase shifts in melatonin rhythm. In natural settings, however, light is a very complex signal. How melatonin responds to weekly- and seasonal-dependent variations in light exposure is still poorly understood. In this talk I will present results from a series of observational and intervention studies on the relationship between melatonin and light exposure in the field.

Aim: Spinal cord injury (SCI) triggers inflammatory response by activation and accumulation radical oxygen species (ROS). Cell therapy has no effective long term recovery outcomes due to presence of ROS in lesion site increase the death rate of transplanted cells.One efficient approach to address this issue is adding adjuvants like neurotrophic factors and antioxidants, among them melatonin has been reported to play a key role in neuroprotectection. The melatonergic treatment is remarkably associated with scavenger oxidative stress and cell proliferation. The purpose of this study is the impac