Research in the Gamm laboratory uses human pluripotent stem cells to study retinal development and degeneration and to develop cell-based rescue or replacement approaches. The intern will culture and differentiate cells, characterize retinal tissues, and learn sectioning, immunohistochemistry and molecular methods. This full-time Waisman Center role lists a salary of $46,109 and a 15 January 2027 start. Apply with a résumé and cover letter to Lindsey Jager at ldjager@wisc.edu, using the subject “Research Intern-Development and Disease Modeling”.
In Biology and Cell Biology
The Research Luke Harland is establishing a new research group based in the Loke Centre for Trophoblast Research within the Department of Physiology, Development and Neuroscience at the University of Cambridge. The group investigates how specialised blood and vascular cell types arise during mammalian development and uses this knowledge to generate defined cell populations from pluripotent stem cells for mechanistic studies and tissue modelling. We aim to understand how developmental history shapes blood and vascular cell identity and function, and to apply this knowledge to build improved vas
Exploring mechanisms of human brain expansion in cerebral organoids
Madeline Lancaster · MRC Laboratory of Molecular Biology, Cambridge
Tue, May 17, 2022 · 15:00 UTC
The human brain sets us apart as a species, with its size being one of its most striking features. Brain size is largely determined during development as vast numbers of neurons and supportive glia are generated. In an effort to better understand the events that determine the human brain’s cellular makeup, and its size, we use a human model system in a dish, called cerebral organoids. These 3D tissues are generated from pluripotent stem cells through neural differentiation and a supportive 3D microenvironment to generate organoids with the same tissue architecture as the early human fetal brai