AASCRM Webinar Series October 2026
Yun Xia · A*STAR Institute of Molecular and Cell Biology, Singapore; RIKEN Center for Biosystems Dynamics Research, Japan
Tue, Oct 13, 2026 · 03:00 UTC
Yun Xia presents macrophage–kidney assembloids that address missing immune and vascular components in stem-cell organoids. Directed differentiation, self-organization, genetic perturbation, xenotransplantation and single-cell analysis reveal immune–epithelial interactions. Macrophages from the same parental cells acquire resident phenotypes; diabetic and polycystic kidney models show context-dependent effects on inflammation, epithelial injury and disease progression. Minoru Takasato addresses kidney organoids’ missing urinary outflow by generating bladder tissue from human pluripotent cells.