Postdoctoral position Small Molecules that Repartition RNA Conformational Ensembles

Study how small molecules redistribute RNA conformational ensembles and alter RNA function in living cells. The project combines high-throughput SHAPE/DMS structure probing, ensemble deconvolution, chemical biology, compound screening and functional assays. The RNA Structural Dynamics Group at GBB offers a one-year full-time appointment, with research crossing structural biology, computation and RNA-targeted drug discovery.

Completed or nearly completed relevant PhD. RNA biochemistry/structure probing, small-molecule interactions and sequencing-data analysis are valuable; computational applicants interested in experimental validation are also encouraged. Strong research output, collaboration and English communication. Apply through the employer form with CV and cover letter by 20 November 2026, 23:59 Dutch local time.