Scientist I/II, Functional Genomics

Lead organoid model development for high-throughput functional genomics and CRISPR screening at an AI-driven drug discovery company. The scientist will build and scale patient-, iPSC- or tissue-derived organoid systems to map genotype-phenotype relationships, optimise culture and characterisation protocols for screening, and work with computational biology and machine learning teams to interpret large functional genomics datasets.

PhD in molecular biology, genetics, cell biology or a related field with 0-4 years of industry or postdoctoral experience. Strong hands-on experience developing and maintaining organoid models and with CRISPR-based perturbation (for example lentiviral or AAV delivery) in 3D systems; familiarity with adapting organoids to high-throughput formats. Perturb-seq, single-cell or spatial omics and Python or R analysis are preferred.