Microbiology podcasts

Nature’s science-prize roundup discusses the research recognised by the 2026 Nobel prizes: light-based control of neurons, detection of cosmic neutrinos and the emergence of handed organic molecules. A further segment examines what gut microbes can reveal about ancient human populations and journeys. Research highlights address young viewers of online sports videos and observations of black-hole jets. The episode connects neuroscience, particle physics and chemistry with evolutionary questions about the human microbiome.

Anna Truzzi and Luca Pellegrino discuss experiments on a historical antibacterial preparation and the sources of bias in AI systems. An external segment with Ian Scott and Ilaria Zanardi explores elephant communication, including low-frequency sound, long-distance signalling and the evidence for individually distinctive calls.

Hosted by Anna Truzzi, Luca Pellegrino

Vincent Racaniello, Alan Dove and Brianne Barker discuss a newly identified mechanism for RNA-guided DNA recognition and genetic control that may predate CRISPR pathways. They also examine research proposing that features of Alzheimer’s disease neuropathology could have originated as a host response to infection in the brain, including evidence concerning phosphorylated tau and herpesvirus activity. The episode connects ancient molecular recognition mechanisms with questions about antiviral defence.

Hosted by Vincent Racaniello, Alan Dove

Vincent Racaniello speaks with Roberto Cattaneo and Kalpana Yadav at the 2026 American Society for Virology meeting about measles persistence in the brain. They discuss selection for highly fusogenic viral variants when usual measles receptors are absent, neuron-to-neuron spread, and the development of subacute sclerosing panencephalitis, a rare, fatal delayed complication of measles infection.

Hosted by Vincent Racaniello

This edition of The Science Show covers extinct big cats and early humans, the material properties behind durable Roman concrete, the history of technological disruption by space weather, and methane-consuming microorganisms living in tree bark.

Hosted by Robyn Williams, Belinda Smith

Adrian Hill discusses the scientific challenges behind developing the R21/Matrix-M malaria vaccine, its path from research to use, and efforts to make vaccination accessible in Africa. The conversation explores the complexity of the malaria parasite and the practical demands of vaccine production and delivery. The publisher credits Marushka Soobben and Chris Smith as presenters and provides the episode audio and interview transcript.

Hosted by Marushka Soobben, Chris Smith

Paul Bieniasz joins Vincent Racaniello, Alan Dove and Kathy Spindler to discuss his laboratory’s research on coronavirus genetic variation. The conversation examines how the NSP15 nuclease cuts viral RNA into short pieces that can be reinserted elsewhere, producing insertion mutations and new furin-cleavage sites at the spike S1/S2 boundary. The episode links the underlying preprint and includes listener correspondence and weekly selections.

Hosted by Vincent Racaniello, Alan Dove

Nature staff discuss an AI tool for assessing the effects of nine billion human genetic mutations, followed by research challenging assumptions about Bunsen burners and contamination near laboratory work areas. This episode is part of Nature Podcast’s Briefing Chat series and is available from the publisher on Acast.

Vincent Racaniello, Kathy Spindler and Brianne Barker discuss research using generative AI to design complete bacteriophage genomes, including reported viable phages active against antibiotic-resistant bacteria. They also examine a study linking recombinant shingles vaccination with lower cardiovascular-event risk. The discussion connects genome modelling, experimental virology and vaccine research, alongside listener letters and weekly selections.

Hosted by Vincent Racaniello, Brianne Barker

Science journalists discuss why the food-borne illness cyclosporiasis is difficult to track and a new map of a major highway in the human nervous system. Leslie Chan then explains an ingestible metabolic probe that detects gut-microbiome enzyme activity from volatile signals in the breath.

The hosts discuss research linking bacterial signatures to colon-cancer recurrence and a separate study of bacteriophage-derived proteins that trigger bacterial pilus detachment. The episode works through the scientific papers and experimental questions; the cancer findings concern an association rather than proof of causation.

Hosted by Vincent Racaniello, Michael Schmidt

Nature's podcast explores genetically engineered probiotic bacteria that sense elevated glucose and release therapeutic factors, lowering blood sugar in animal studies. The episode also covers ecological research on pumas, geological erosion, and how a solar eclipse can help researchers probe the Sun's magnetic corona.

The hosts discuss nitrogen fixation in a marine alga and the evidence for a nitrogen-fixing organelle. Related topics include plastic pollution, antimicrobial resistance and the rumen microbiome. The episode links microbial evolution and physiology with marine nutrient cycling.

Hosted by Vincent Racaniello, Michael Schmidt

Nature journalists discuss a chemical route that converts PVC waste into motor lubricant and engineered yeast that produces a potential cancer drug.

Bonnie Bassler explains how bacteria detect signals from their surroundings and coordinate behaviour through quorum sensing. Chemical communication allows microbes to sense nearby populations and undertake collective activities that individual cells could not accomplish alone. The discussion examines bacterial information processing and the consequences of these coordinated behaviours, including within the human body.

Hosted by Sean Carroll

Melissa and Jam examine wool, lanolin and claims about resistance to odour and bacteria. The episode connects their chemical structures with water-repelling behaviour, processing and interactions with microbes, distinguishing observed odour reduction from broader claims about antimicrobial activity.

Hosted by Melissa, Jam

Charlene Lancaster speaks with Cesar de la Fuente about using artificial intelligence to discover novel antibiotics from organisms and genetic sources spanning spiders, archaea, woolly mammoths, and humans.

Markus Covert discusses comprehensive bacterial cell simulations and what whole-cell modelling could contribute to future studies of neurons.

Lars Bakken discusses using bacteria to reduce nitrous-oxide emissions associated with agricultural fertilizer. Conversation in Norwegian.

Will Ratcliff investigates the transition from independent cells to multicellular organisms through long-term evolution experiments. His snowflake-yeast model lets researchers watch cooperative structures emerge, test ideas about biological complexity and assess the strengths and limitations of laboratory approaches to a major evolutionary transition.

Hosted by Janna Levin, Steven Strogatz