Genome architecture and phenotype
Video page · Apr 4, 2025
Alexandre Reymond, Professor, Centre intégratif de génomique, University of Lausanne, Switzerland
Genetic architecture of polygenic traits and diseases
Genetics, Genetic Epidemiology, Medical Genetics and seminar by Lluis Quintana-Murci, Professor at the Collège de France
Hosted by Collège de France
Friday 09:30–11:00 Paris (GMT+1)
Recording available
Amphithéâtre Marguerite-de-Navarre, Site Marcelin-Berthelot · In person
Abstract
This lecture examines traits and diseases influenced by many genetic variants. It introduces genome-wide association studies, pleiotropy and polygenic risk scores, then considers their use in precision medicine. Outstanding limitations include unexplained heritability and the uneven representation of human populations in genomic research.
Topics
traitsdiseasesgenetic variantsgenome-wide association studiespleiotropypolygenic risk scoresprecision medicineunexplained heritability
Show 2 more topics
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