Logic and grammar of " enhancer "sequences
Video page · Mar 21, 2025
Denis Duboule, Professor at the Collège de France
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Genetics, Molecular Biology, Molecular Genetics and seminar by Denis Duboule, Professor at the Collège de France
Hosted by Collège de France
Friday 10:00–11:30 Paris (GMT+1)
Recording available
This lecture examines the sequence features through which enhancers bind transcription factors and control gene expression. It introduces computational approaches, including neural networks, for recognising regulatory DNA and potentially designing synthetic elements. It also compares recurring arrangements of enhancers around genes important in mammalian development.