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Seminar, Hosted by Collège de France

Hox genes and tail formation ; a global approach

Denis Duboule

Professor at the Collège de France

Abstract

This lecture compares two approaches to the evolution of mammalian tails. It critically examines the proposed role of altered Tbxt splicing in ape tail loss, including difficulties interpreting mouse experiments. It then introduces quantitative-genetic studies of deer mice in different habitats, where several loci contribute to variation in tail length.

Topics