Evolution of control sequences
Genetics, Molecular Biology, Molecular Genetics and seminar by Denis Duboule, Professor at the Collège de France
Hosted by Collège de France
Friday 10:00–11:30 Paris (GMT+1)
Recording available
Amphithéâtre Guillaume-Budé, Site Marcelin-Berthelot · In person
Abstract
This lecture examines how regulatory DNA contacts its target genes through both CTCF-dependent and other mechanisms. It then considers diseases caused by disrupted enhancer function, ranging from missing elements to genomic rearrangements that alter regulatory contacts. Transposable elements are discussed as contributors to the evolution of gene regulation.
Topics
regulatory DNAtarget genesCTCFenhancer functiongenomic rearrangementsregulatory contactstransposable elementsgene regulation
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