Hox genes and tail formation ; a global approach
Video page · Mar 20, 2026
Denis Duboule, Professor at the Collège de France
The disappearance of the tail in great apes
Genetics, Evolution, Evolutionary Biology and seminar by Denis Duboule, Professor at the Collège de France
Hosted by Collège de France
Friday 10:00–11:30 Paris (GMT+1)
Recording available
Amphithéâtre Guillaume-Budé, Site Marcelin-Berthelot · In person
Abstract
This lecture traces research on the mouse T locus and the Tbxt gene before examining a proposed mechanism of tail loss in apes. A repeated DNA insertion may alter splicing and protein production. The discussion asks how a small genetic change could affect development and generate a large, persistent evolutionary transformation.
Topics
Show 1 more topic
evolutionary transformation
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