Coevolutionary processes in the adaptive immune system
Video page · Aug 20, 2020
Armita Nourmohammad, University of Washington
Understanding the Mysteries of the Cell: Our Immune Repertoire Viewed Through the Darwin's Eyes
Immunology, Evolution, Evolutionary Biology and seminar by Stephen Quake, D. Phil. Lee Otterson Professor. Bioengineering and Physics, Stanford University
Hosted by Collège de France
Monday 17:00–18:00 Paris (GMT+2)
Recording available
Amphithéâtre Maurice-Halbwachs, Site Marcelin-Berthelot · In person
Abstract
Stephen Quake examines antibody repertoires as populations shaped by diversification and selection. Recombination, junctional changes and mutation create many potential antibodies, but their realised diversity and similarity between individuals remain important questions. High-throughput sequencing in humans and model organisms is used to study these patterns and evolutionary convergence.
Topics
antibody repertoiresRecombinationjunctional changesmutationrealised diversityhigh-throughput sequencingmodel organismsevolutionary convergence
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