Study of the effect of positive and negative correlations on functional connectivity disruption in MCI
Ignacio Taguas · Neuromatch 5
Wed, Sep 28, 2022
INTRODUCTION Graph theory is a state of the art approach to assess functional connectivity (FC) disruption in neurological disorders. However, this methodology does not allow distinction between positive and negative FC correlations; negative correlations, or anticorrelations, are usually either discardes or taken as positive values, and therefore its influence is rarely studied. RESEARCH QUESTION In the present study, we used magnetoencephalography (MEG) to construct cross-frequency networks, and studied the positive and negative correlations independently and jointly, to evaluate the contri