In situ structural biology: bridging molecular mechanisms with system-wide approaches

The workshop integrates cryo-electron tomography, fluorescence microscopy, mass spectrometry and computational modeling to investigate macromolecular complexes within intact biological systems. Sessions connect molecular machines with organelles, whole cells and multicellular interactions, emphasizing complementary data and methods that preserve native context. It welcomes experts and early-career life scientists interested in advanced imaging and system-wide analysis. On-site sessions start at 13:30 on 9 February and finish at 12:30 on 12 February, Europe/Berlin time. On-site registration closes on 5 January; virtual registration closes on 2 February 2027. Virtual attendance includes live talks, questions and time-limited access to recordings where speakers permit.