Structural Biology jobs

Build computational infrastructure and data workflows for de novo protein design. The scientist develops instrument-to-analysis pipelines and protein databases, connects sequence and structural models with experimental measurements, contributes machine-learning models, and advises researchers on reproducible computational workflows. The full-time, 37-hour…

VIB’s Center for AI and Computational Biology and KU Leuven’s Department of Human Genetics seek a group leader and professor developing AI and mechanistic mathematical models for biological questions. Potential themes include hybrid mechanistic and deep-learning models, genome-regulation foundation models, single-cell and spatial multi-omics, protein…

VIB.AI and KU Leuven seek a group leader and professor developing AI and mechanistic models for biological research. Possible areas include genome-regulation foundation models, protein structure and interactions, cellular imaging, disease models, digital twins and experimental feedback. The role combines independent research, supervision, teaching and…

Contrat doctoral de 36 mois à l’ENS de Lyon, début prévu le 1er janvier 2027, rémunéré 2 300 euros brut mensuel. Le projet PREBACTOR vise à comprendre la prédation bactérienne chez Myxococcus xanthus. La thèse construira un réseau d’interactions entre les protéines des appareils Kil et T3SS* avec des méthodes de prédiction structurale par réseaux de…

The Loerch laboratory studies neuronal ribosomes and protein synthesis. The intern will organize structural datasets, build reproducible analysis software, compare structural features, and investigate ribosome states in cellular cryo-EM images using two-dimensional template matching. Machine learning may form part of the work. The appointment is up to 20…

Assistant Project Scientist in the structural biology of microtubule motors and regulatory proteins. The researcher will develop experiments and analyses involving molecular biology, biochemical reconstitution, cryo-electron microscopy sample preparation and imaging, single-particle structure determination using Relion and Cryosparc, and molecular model…

The Institute for Neurodegenerative Diseases at UCSF, in the Sandler Neurosciences Center at Mission Bay, studies how the conformational heterogeneity, maturation and transmission of proteopathic assemblies (prions) of tau, amyloid-beta and alpha-synuclein differ across neural cell types and diseases. The Professional Researcher helps manage and contributes…

Investigate uncharacterised biological systems such as Fanzor and TIGR-Tas and engineer them as molecular tools. Research approaches include cryo-electron microscopy, molecular phylogenetics and sequencing-based functional analysis.

Provide experimental support for research on neurological and psychiatric disease mechanisms. The laboratory studies abnormal protein aggregation and disturbances in RNA translation.

RIKEN’s Life and Medical Science Application Interface Platform Development Unit, led by Yasuhiro Matsunaga, seeks postdoctoral researchers for the TRIP-AGIS project. Research integrates biomolecular simulation with AI: agents that plan and execute reproducible simulation workflows; molecular-dynamics surrogates with physical-validity and…

Develop deep-learning methods for generative protein design at the interface of machine learning, molecular simulation, structural biology and experimental protein engineering. Projects can investigate conformational ensembles, integrate protein language models with physics, or design proteins for challenging membrane and sugar interfaces. The researcher…

Study how giant Starship transposons mobilize and carry virulence genes in plant-pathogenic fungi. The project offers either a cell-biology track investigating transposon movement in living fungal cells or a biochemical and structural track reconstituting and characterizing the responsible proteins. The postdoc collaborates with a complementary genomics…

Investigate how E3 ubiquitin ligases recognise and modify substrates in the Nile Lab. Independent projects combine protein purification, quantitative mechanistic studies and in-vitro reconstitution with structural biology, chemical biology, selection methods and cellular experiments to understand and redirect ubiquitin signalling.

Develop computational biology research that advances the scientific usefulness of AI systems. Work may span large-scale sequence analysis, structural biology, phylogenomics and screening datasets, with analysis pipelines that inform experimental hypotheses and AI-agent evaluation. The advertised annual salary is USD 300,000–320,000. Anthropic’s hybrid…

Lead computational work on protein structure, design and antibody discovery. Develop methods that connect protein foundation models, antigen and binder datasets, biophysical prediction and experimental results, while building reliable data workflows and GPU-enabled tools. The position includes team leadership and collaboration with laboratory scientists.…

Develop computational algorithms and software that integrate high-performance computing with experimental imaging, scattering and time-resolved data to study biomolecular dynamics. The Computational Structural Biology Research Team collaborates with experimental groups on biologically relevant molecules. Appointments begin on or after 1 October 2026, with…

Melody is recruiting a protein engineer to create biosensors from allosteric switches, signaling motifs, reporter proteins, site-specific chemical modifications, and bioelectronic interfaces. The role spans construct design, wet-lab screening, device integration, experimental or computational protein design, and mentoring within a continuous…