15 results
Build computational infrastructure and data workflows for de novo protein design. The scientist develops instrument-to-analysis pipelines and protein databases, connects sequence and structural models with experimental measurements, contributes machine-learning models, and advises researchers on reproducible computational workflows. The full-time, 37-hour…
The Max Planck School of Biomedical Artificial Intelligence is recruiting its first cohort for 25 fully funded, structured three-year PhD positions at the interface of AI and the life sciences. Doctoral researchers will develop computational and AI methods for molecular and cellular systems, protein and molecule design, complex biological traits and neural…
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Lead discovery of lipid nanoparticle systems that deliver RNA beyond the liver. The director coordinates lipid chemistry, formulation, protein design and bioconjugation with cell-based assays and animal studies. Responsibilities include translating delivery research across species, directing a research team and shaping scientific publications and…
Develop new gene insertion approaches and engineered immune-cell therapies in the CRISPR-X research team. The scientist designs genome editing experiments and CAR-T constructs, evaluates molecular and cellular outcomes, and develops translational assays for new disease indications. Methods include cloning, quantitative and digital PCR, sequencing and…
A January–June 2027 placement with the Biotherapeutics Discovery team in Cambridge, Massachusetts. Work focuses on evaluating and improving therapeutic antibodies and VHH candidates through binding, biophysical and cell-based assays. Activities include protein production and purification, mammalian cell culture, ELISA, Octet measurements, size-exclusion…
Develop deep-learning methods for generative protein design at the interface of machine learning, molecular simulation, structural biology and experimental protein engineering. Projects can investigate conformational ensembles, integrate protein language models with physics, or design proteins for challenging membrane and sugar interfaces. The researcher…
Develop high-throughput methods to measure how protein interactions respond to mechanical force. The project combines protein engineering, yeast surface display, directed evolution, deep sequencing and single-molecule force measurements, with machine-learning models trained on the resulting data. Initial applications study interactions involved in blood…
Connect therapeutic-antibody discovery with computational design. The scientist develops and validates rational antibody designs, structures experimental data to improve models, and collaborates with wet-lab and machine-learning teams on humanisation, affinity, specificity and developability.
Develop synthetic biological tools that make multicellular behaviour predictable and programmable within the Cell Science accelerator. Pursue questions about synthetic tissues and cell behaviour, using stem-cell engineering, high-content microscopy, molecular engineering and quantitative modelling. Collaborate with scientists and project specialists. The…
Lead the proteome-editor experimental team in the Allen Institute AI BioDesign initiative. Build a rapid design–test–learn pipeline for de novo protein degraders, oversee cell-based library screening and degrader evaluation, and partner with machine-learning researchers on active learning and model-ready datasets. The role combines scientific programme…
Lead computational work on protein structure, design and antibody discovery. Develop methods that connect protein foundation models, antigen and binder datasets, biophysical prediction and experimental results, while building reliable data workflows and GPU-enabled tools. The position includes team leadership and collaboration with laboratory scientists.…
Two faculty vacancies advertised together, with tenure-track or tenured appointments expected for the 2027–28 academic year. Develop an independent funded research programme using biochemical, computational and AI approaches to protein, enzyme, metabolic or nucleic-acid engineering. Environmental applications include carbon capture, remediation, biosensors…
Three-year, full-time doctoral research position applying language-model interpretability to protein function. The computational project will study how protein language models represent biological properties, build immunogenicity classifiers and help steer protein generation, in collaboration with experimental researchers. The role is funded at TV-L E13 and…
Melody is recruiting a protein engineer to create biosensors from allosteric switches, signaling motifs, reporter proteins, site-specific chemical modifications, and bioelectronic interfaces. The role spans construct design, wet-lab screening, device integration, experimental or computational protein design, and mentoring within a continuous…
Melody is hiring a bioelectronics engineer to integrate protein biosensors, surface chemistry, hydrogels, membranes, and optical or electrochemical readout hardware into continuous molecular-monitoring technology. The role owns wetware integration strategy, diagnostic experimentation, directed-evolution workflows, materials development, instrumentation, and…
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