Topic: cancer

Support NSW organisations recruiting outstanding health and medical research leaders from overseas. Proposals should establish a strategically important research programme with a clear route to translation. Cardiovascular research and projects exclusively focused on cancer are outside this call.

Neural crest cells and cranial placodes share developmental and evolutionary origins while producing diverse tissues and sensory structures. The conference examines their roles in vertebrate development, regeneration and disease, including congenital abnormalities, cancer and sensory dysfunction. Researchers will compare model organisms and experimental approaches, connecting genomic, transcriptomic and proteomic findings with cell behaviour and tissue formation. Discussion will focus on mechanisms of normal development and the origins of disorders when those processes fail. Attendance applica

This conference examines the origins, distribution and consequences of mutations across cells, tissues, organisms and populations. Improved sequencing accuracy, experimental perturbations, multi-omic measurements and computational analysis are brought together to study genetic heterogeneity and its effects on genome function, evolution and disease. Sessions address mechanisms of mutagenesis, technologies for detecting and interpreting mutations, variation across the tree of life, tissue-level diversity, and evolutionary dynamics in cancer and other diseases. Researchers from genomics, mutagene

T-cell engagers can be developed for both cancer and autoimmune disease, but differences in target cells, disease biology and therapeutic goals require different preclinical strategies. Wanjun Yuan and Haiqiao Sun compare model selection and evaluation endpoints, from T-cell engagement and tumour killing to B-cell depletion, immune reconstitution and safety. A case-based exchange examines how the same target may call for different studies across indications, including assessment of cytokine-release signals and the effects of dose and exposure on experimental design.

This EMBO Workshop connects organelle contact sites and cytoskeletal interactions with metabolism, signalling, and trafficking, and examines their relevance to neurodegeneration, cancer, and other diseases.

Fund pilot studies and early research addressing public-health priorities, including infectious disease, AI diagnostics, digital health, cancer, maternal health, mental health and healthy ageing. Proposals should generate evidence useful for health policy and practice. Submit the English EOI, budget and investigator CVs together as one PDF by 2 October 2026, 18:00 EAT. The linked Google submission form requires sign-in.

Stephen Quake describes how circulating cell-free nucleic acids became a basis for non-invasive diagnostics. Combining genome knowledge with high-throughput sequencing made liquid biopsies useful in pregnancy, transplantation, infection and cancer. The lecture follows the development of blood-based tests that can replace some invasive tissue-sampling procedures.

Stephen Quake revisits the origins of genetic variation, connecting classic bacterial experiments with modern single-cell genomics. The lecture asks how mutations accumulate during human life, how they contribute to cancer and how tumour evolution can be reconstructed. It illustrates how measurements of individual cells help address these questions.

Pluripotent cells, including embryonic stem (ES) and induced pluripotent stem (iPS) cells, are used to investigate the genetic and epigenetic underpinnings of human diseases such as Parkinson’s, Alzheimer’s, autism, and cancer. Mechanisms of somatic cell reprogramming to an embryonic pluripotent state are explored, utilizing patient-specific pluripotent cells to model and analyze neurodegenerative diseases.

Heather Harrington explains topological data analysis and the construction of barcodes that summarize the shape of a dataset across scales. She describes how these tools reveal structure in complex information and how they can support studies of proteins and diseases such as cancer. The interview was recorded at the European Congress of Mathematics.

Jarle Breivik discusses cancer as a biological process and critically examines expectations of a universal cure. Conversation in Norwegian.

Nick Lane traces how a metabolic cycle that converts gases into organic molecules and back can connect major transitions in the history of life. The lecture links this chemistry to the origin of life, photosynthesis and the emergence of animals, and considers its connections with cancer and the emergence of consciousness.

Cancer-related fatigue is a prominent and debilitating side effect of cancer and its treatment. It can develop prior to diagnosis, generally peaks during cancer treatment, and can persist long after treatment completion. Its mechanisms are multifactorial, and its expression is highly variable. Unfortunately, treatment options are limited. Our research uses syngeneic murine models of cancer and cisplatin-based chemotherapy to better understand these mechanisms. Our data indicate that both peripherally and centrally processes may contribute to the developmental of fatigue. These processes includ

Life of biological molecules spans time and length scales relevant at atomic to cellular time and length scales. Hence, novel molecular modeling approaches are required to be inherently multi-scale. Here we describe multiple methodologies developed in our laboratory: rapid discrete molecular dynamics simulation algorithm, protein design and structural refinement tools. Using these methodologies, we describe therapeutic strategies to combat this HIV and cancer, as well as design novel approaches for controlling proteins in living cells and organisms.

Cancer remains a significant challenge in the medical field (Siegel et al., 2012). Conventional treatments frequently have serious side effects that lower patients' quality of life and cannot totally eradicate the disease (Hendijani, 2015). Additionally, neural progenitor cells might be adversely affected by chemotherapeutic drugs, extinguishing any possibility of nervous tissue regeneration (Dietrich et al., 2006). This emphasizes the importance of precisely targeting cancer cells while preserving healthy brain cells. This work aims at addressing this challenge through the development of poly